Julianne Moore's huge Golden Globes win on Sunday night shocked fans who expected Reese Witherspoon to win in the Best Actress in a Motion Picture - Drama category. Beating out fellow nominees Rosamund Pike, Felicity Jones and Jennifer Aniston, Moore is one step closer to winning the coveted Oscar. 

Moore wowed critics and audiences alike with her performance as a mother who is diagnosed with early on-set Alzheimer's Disease. Still Alice pulled at our heartstrings with a look at this diagnosis through the eyes of someone who sees the effects it has on her and her family. 

“Oh my goodness! Oh my goodness!” exclaimed Moore as she took the stage in her glittering Givenchy dress. “No one wanted to see a movie about a middle aged woman, so I want to thank the people who made this movie.”

Julianne Moore Still Alice Julianne Moore's performance in 'Still Alice' is said to be a career best. Will it be enough to beat the likes of Reese Witherspoon in 'Wild' and Felicity Jones in 'The Theory of Everything'?

Prior to the big reveal, Moore and Witherspoon seemed like they were neck and neck for the Best Actress statuette. It really was either actress’ game. Critics from outlets such as Vanity Fair, Nerdist and Indiewire praised Wild as the best performance of Witherspoon’s career. Still Alice, on the other hand, was hailed for its unique look at Early-Onset Alzheimer's Disease and Moore for her subtle and realistic portrayal. 

In addition, Aniston impressed critics with her significant transformation. Cake saw the actress take on a more serious role as a woman suffering chronic pain who becomes infatuated with a woman who committed suicide. The film, in general, didn’t earn a great deal of praise, though. Jones and Pike, however, drastically elevated their respective films.

Kristen Stewart Julianne Moore Still Alice Both Kristen Stewart and Julianne Moore are receiving high acclaim for their roles in 'Still Alice.' The two sparkled at a special screening for the film at AFI Fest.

While Jones held her own alongside Redmayne in The Theory of Everything, Pike’s performance as “Amy Amy” Dunne in Gone Girl was one of the most haunting and sadistic female villains of modern cinema. 

Moore and Witherspoon will surely duke it out next in the upcoming Oscar race, though Moore's win has set her far ahead of the pack. The nominees will be officially announced the morning of Jan. 15. While the latter has already earned an Oscar for Best Actress for her role in Walk the Line, the former hasn’t. Moore has been nominated four times so far and hasn’t won yet!  

Jones and Pike are likely to score nominations, though Aniston remains a question mark. Amy Adams in Big Eyes, Marion Cotillard in the under-the-radar film Two Days, One Night, or Hilary Swank in The Homesman could snag Aniston's spot.